MCQ ON TRANSGENIC ANIMALS class 12 for NEET | TRANSGENIC ANIMALS class 12 | MCQ TRANSGENIC ANIMALS with Answer | Check the below NCERT MCQ question for class 12 Biology based on the with Answers.
MCQ on TRANSGENIC ANIMALS class 12 Biology with answers were prepared based on the latest pattern.We have provided class 12 Biology MCQs question with Answers to help students understand the concept very well.
MCQ ON TRANSGENIC ANIMALS class 12 for NEET
MCQ ON TRANSGENIC ANIMALS is useful for NEET / CSIR / UGC / CBSE / ICSE / AIIMS / EXAM / AFMC EXAM / STATE LEVEL MEDICAL EXAM/ KVS PGT BIOLOGY / NVS PGT BIOLOGY EXAM 2022-23 , 2023-24
INTRODUCTION:-
TRANSGENIC ANIMALS
Animals that have had their DNA manipulated to exposes and express foreign genes are known as transgenic animals.
Transgenic mice, rabbits, pigs,sheep ,cows and fish have been produced, although over 95 % of all existing transgenic animals are mice.
Why are these animals being produced ? How can man benefit from such modifications .
Normal physiology and development: transgenic animals can be specifically designed to allowed study of how geans are regulated and how they affect the normal functions of the body and it’s developments for example study of complex factors involved in growth such age insulin like growth factor.
By introducing gene from the other species that elder the functions of this factor and studying the biological effects that result information is obtained about the biological role of the factor in the body.
Study of disease:-many transgenic animals are designed to increase our understanding of how genes contribute to the development of disease.
Dzire specially made to serve as models for human disease so that investigation of new treatment for disease is made possible.
Today transgenic models exist for many human diseases such age cancer cystic fibrosis rheumatoid arthritis and Alzheimer’s.
Biological products:- medicines required to treat certain human disease can contain products but such products are often expensive to make.
Transgenic animals that produce each full biological products can be created by introduction of the portion of DNA or genes which codes for a particular products such as human protein Alpha One antitrypsin used is to treat emphysema.
Similar attempts are being made for treatment of phenylketonaria (PKU) and cystic fibrosis.
In 1997, the first transgenic cow roji produce human protein in rich milk 2.4 grams per litre. Tamil content the human Alpha electrolyte and watch nutritionally more balance products for human babies than natural cow milk.
Vaccine safety:-transgenic mice are being developed for each in testing of vaccines before they are used on humans.
Transgenic mice are being used to taste the safety of the polio vaccine.
If successful and found to be reliable they could replace the use of monkeys to taste the safely of batches of the vaccine.
Chemical safety testing:-this is known as toxicity or safety testing.
The procedure is the same as that is for testing toxicity of drugs. Transgenic animals are made that carry jeans which make them more sensitive talks to toxic substances then non transgenic animals. They are then exposed to their toxic substances and effects studied.
Molecular diagnosis:
You know that for effective treatment of a disease , early diagnosis and understanding it’s pathophysiology is very important.Using conventions methods of a diagnosis serum and urine analysis is not possible.
Recombinant DNA technology , Polymerase Chain Reaction (PCR) and Enzyme linked Immuno sorbent Assay (ELISA) are some of the technique that serve the purpose of early diagnosis.
Presence of a pathogen bacteria , virus etc is normally suspected only when the pathogen has produced a disease symptoms.By this time the concentration of pathogen is already very high in the body.
However , very low concentration of a bacteria or viruses at a time when the symptoms of the disease are not visible can be detected by the amplification of their nucleic acid by PCR.
PCR is being used to detect mutations in genes in suspected cancer patients too.It is a powerful technique to identify many other genetic disorders.
gene therapy
The improved techniques for gene manipulation and deeper understanding of gene function in the body,may someday enable the medical biotechnology to correct gene disorders in humans. Treatment of a genetic disorder by manipulating gene is called gene therapy.
Gene therapy has not so far given any province relief to patients, contrary to some claims in the media.
Genetic disorder caused by a a single defective allele can be theoretically set write by replacing or supplementary the defective allele with a normal functional allele the recombinant DNA technology.
The new allele could be inserted into the bone marrow cells this cells keep multiplying through out the patients life and this would enable the transpilanted allele to be replicated and continually expressed.
Bone marrow cells give rise to all the cells of the blood and immune system.
The immune system may then counter the disease.
The genetic disease that are being investigated for gene therapy range from sickle cell anaemia to savere combined Immuno deficiency (SCID).
The SCID patient has a defective gene for enzyme adenosine deaminase (ADA). He or she lacks functional T – lymphocytes and their fails to fight the infecting pathogens.
Lymphocytes are extracted from the patients bone marrow and normal function copy of human gene coding for ADA is introduced into this lymphocytes with the help of retrovirus.
The cells so created are re introduce into the patient’s bone marrow.
The lymphocytes produced by this cells contain functional ADA gene and reactivate the victims immune system for life.
MCQ TRANSGENIC ANIMALS class 12 for NEET/KVS PGT BIOLOGY / NVS PGT BIOLOGY EXAM 2022-23, 2024.
1. Animals that have their DNA manipulated to possess and express
an foreign genes are known as
(a) Transgenic animals
(b) Polymerase Chain Reaction
(c) molecular diagnosis
(d) Recombinant DNA technology
Ans (a) Transgenic animals
2. Which have been produced by transgenics
(a) rat and fish
(b) rabbits
(c) pigs ,sheep ,cows
(d) all the above
Ans. (d) all the above
3. Over 95 % of all existing transgenic animals are
(a) rat
(b) monkeys
(c) mice
(d) rabbits
Ans. (c) mice
4. Transgenic animals are used for
(a) study of disease
(b) biological products
(c) vaccines safety
(d) all the above
Ans.(d) all the above
5.To test the safety of the polio vaccine , which transgenic animals are used to
(a) transgenic rabbits
(b) transgenic mice
(c) Transgenic pigs
(d) transgenic monkeys
Ans.(b) transgenic mice
6. Which are being developed for each in the testing the safety of vaccines before they are used on humans ?
(a) ELISA
(b) Eastern blot
(c) PCR
(d) Transgenic mice
Ans.(d) Transgenic mice
7. Human Protein used to treat emphysema.
(a) DNA replication
(b) alpha – 1 – antitrypsin
(c) gamma- 1 trypsin
(d) beta – 1 – trypsin
Ans.(b) alpha – 1 trypsin.
8. The first Transgenic cow is
(a) Dolly
(b) sahiwal
(c) Rosie
(d) Jersey
Ans.(c) Rosie
9. Rosie produced human Protein – enriched milk is …….per litre
(a) 3.4 grams
(b) 2.4 grams
(c) 4.4 grams
(d) 1.4 grams
Ans. (b) 2.4 grams
10. First Transgenic cow Rosie produced protein enriched milk contains the human
(a) A non-functional ADA
(b) A functional ADA cDNA
(c) beta lactalbumin
(d) alpha lactalbumin
Ans. (d) Alpha – lactalbumin
11. If successful and found to be reliable , they could replace the use of …….to test the safety of batches of the vaccine.
(a) rat
(b) monkeys
(c) mice
(d) none of the these
Ans.(b) monkeys
12. Which are not correctly marched:
a) Mice : Mostly existing transgenic animals
b) Rosie : first Transgenic cow
c) Dolly : the first clone organism
(a) a and b
(b) c only
(c) b and c
(d) a , b and c
Ans . (d) both a , b and c
13. Today transgenic models exists for many human diseases
(a) cancer
(b) cystic fibrosis
(c) rhematoid arthritis
(d) All the above
Ans.(d) All the above
14. Testing toxicity of drugs used for
(a) chemical safety testing
(b) physical therapy
(c) biological safety testing
(d) none of these
Ans. (a) chemical safety testing
15. Which is not correct ?
(a) transgenic animals have extra foreign genes
(b) transgenic mice are used in testing vaccines safety
(c) Dolly a first Transgenic cow
(d) Rosie is the first Transgenic cow
Ans.(c) Dolly a first Transgenic cow
ALSO READ:-
● YOU CAN WATCH BIOLOGY SIR Youtube channel
16. Transgenic animals are used for
(a) getting biological products
(b) normal physiology and development.
(c) vaccines safety
(d) all the above
Ans.(d) all the above
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