Pancreatic enzymes for cystic fibrosis and treatment
As we know that cyclic fibrosis is an genetical inherited disorder coming from birth in children that causes sever damage to digestive systems pancreas and intestine,lungs and other important organ in the body.
Cystic fibrosis affects the pancreatic cells that produces pancreatic juices containing various types of Carbohydrates, fats and protein digestive enzyme.
this pancreatic material are very thin and slippery in nature, but in case of people suffering from cystic fibrosis affect the pancreas due to defective genes and secrets sticky and thick pancratic juices, loosing their lubricant and slippery nature that’s form thick wall inside pancreatic duct that block the tube that prevents the discharge of pancreatic juices which are necessary for digestion.
Pancreatic enzymes for cystic fibrosis
So in the process of pancreatic enzymes for cystic fibrosis treatment about 90% of people who are suffering from cystic Fibrosis, they should take pancreatic enzymes before taking their meals and diet. Due to inability of discharge of pancreatic juices person who are suffering from cystic fibrosis in digestive systems there is deficiency in pancreatic enzymes that is known as pancreatic deficiency.
Pancreatic deficiency adversely affect in digestion of carbohydrate proteins and lipids. So pancreatic enzymes for cystic fibrosis treatment should be given as supplement and taken orally before meal known as pancreatic enzyme replacement therapy.
Pancreas enzymes for cystic Fibrosis consist of carbohydrates fats and protein digestive enzymes. Pancreatic juices content sodium bicarbonate and 3 Pro enzymes like trypsinogen, chymotrypsinogen and procarboxypeptidase which are necessary for digestion of proteins.
Pancreatic enzyme used for cystic fibrosis consist of carbohydrate digestive enzyme like like pancreatic amylase
Pancreatic enzymes for cystic fibrosis consists of lipids digestive enzyme known as pancreatic lipase
So all pancreatic enzymes supplements for cystic fibrosis treatment consists of carbohydrate digestive enzymes, protein digestive enzymes, lipid digestive enzymes and nuclic acid digestive enzymes should be given orally in form of capsule before taking meal that is known as pancreatic enzyme replacement therapy for cure of cystic Fibrosis.
Digestive enzymes for cystic fibrosis
People suffering from genetical disorder cystic fibrosis not only effect pancreas of digestive system but it also effect small intestine. And due to defective genes in cystic fibrosis both pancreatic duct and intestinal duct are blocked and their secretion is adversely affected leads to digestive enzyme deficiency.
As we know that both pancreas and intestine are responsible for digestion of all macromolecules like Carbohydrate protein and lipid. And people who are suffering from cystic fibrosis have digestive enzyme deficiency, digestive enzyme supplement containing carbohydrates fats and protein digestive enzymes given to patient and taken as oral before taking meal.
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Digestive enzymes for cystic fibrosis consists of all carbohydrate protein lipid and nucleic acid DNA, RNA digestive enzyme.
But cystic fibrosis is progressive in nature and requires daily care, people with CF are usually able to attend school and doing own work. They often have a better quality of life than people with CF had in previous decades.
Improvements in screening of CF and treatments mean that people with CF now may live into their mid- to late 35 to 45 years and some are living into their 50 years.
Pancreatic enzymes supplements for cystic Fibrosis
The digestive enzymes are taken by mouth in a capsule by pancreatic enzyme replacement therapy. They are distributed throughout the digestive systems and intestines and help digest food and absorb nutrients in order to keep the body healthy.
Each person require a different amount of enzymes according to age and their metabolism, so these levels must be checked and determined by a healthcare practitioner. The enzymes work for about 45 to 60 minutes after being taken.
Pancreatic enzymes supplements for cystic fibrosis there are several brands of enzymes available in different strengths, all of them containing three digestive enzymes for the digestion of fats molecule, for the digestion of protein molecules and amylase for the digestion of carbohydrate and hence Lipase digests fat, protease digests protein, and amylase digests carbohydrates. Fat is the most difficult for the body to digest, so lipase is the enzyme that must be dosed most accurately.
Pancreatic enzymes should be taken with all meals, snacks, and drinks that contain fat. Some foods do not require enzyme supplements, such as fruit (except avocado) and vegetables, sugar, jam, honey and syrup, fruit juice, fizzy drinks, sorbet, jelly and boiled sweets, and juice-based supplements.
Symptoms due to lack of pancreatic enzymes in case of cystic fibrosis
If the enzymes are not taken, or taken dose is not adequate, it can lead in the short term to poorly digested food that causes gas, pain, and unpleasant smells, along with constipation or frequent stools. In the long term, a higher body weight is related to better lung function, further emphasizing the importance of taking the enzymes with all meals.
Side effect of pancreatic enzyme supplement
Taking too many enzyme supplements leads to side effects may cause damage to the intestines, but taking fewer than needed can keep nutrients from being fully absorbed. In very high doses, excess uric acid can occur, although this condition is rare. If excessively high doses are needed, the enzyme efficacy can be improved by using a proton pump inhibitor or H2 antagonist to reduce gastric acid production.
symptoms of cystic fibrosus
Cystic fibrosis signs and symptoms vary depending on the severity of the disease and age. Even in the same person, symptoms may worsen or improve as time passes.
Some people may not experience symptoms until their teenage years or adulthood. People who are not diagnosed until adulthood usually have milder disease and are more likely to have atypical symptoms, such as recurring bouts of an inflamed pancreas is known as pancreatitis, infertility and recurring pneumonia.
Digestive signs and symptoms
The thick mucus can also block tubes that carry digestive enzymes from your pancreas to your small intestine. Without these digestive enzymes, your intestines aren’t able to completely absorb the nutrients in the food you eat. The result is often:
1) Foul-smelling, greasy stools,Poor weight gain and growth, Intestinal blockage, particularly in newborns known as meconium ileus
2) Chronic symptoms or severe constipation, which may include frequent straining while trying to pass stool, eventually causing part of the rectum to protrude outside the anus is known as rectal prolapse
Cystic fibrosis requires consistent, regular follow-up with your doctor, at least every three months. Contact you doctor if you experience new or worsening symptoms, such as more mucus than usual or a change in the mucus color, lack of energy, weight loss, or severe constipation.
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